Neurosurgery and Spine

Neurosurgeons and spine specialists operate in some of the most unforgiving environments in medicine. Delicate anatomy, compromised tissue, and the potential for life-altering complications demand absolute precision.

Our advanced grafts are designed to:^1-4

Maintain native extracellular matrix and signaling components
Provide flexible options in both cryopreserved and lyopreserved formats for surgical flexibility
Conformable, strong, and suited to a range of neurosurgical and spinal techniques

Case studies

Pseudomeningocele

Pre-op

Pre-op X-ray

MRI with CSF collection

Intra-op

Complete excision and hardware replacement

Intra-op

Intra-op STRAVIX◊ Tissue application

Muscle flap closure

One month post-op

A 57-year-old female with a complex medical history, including diabetes, hypertension, atrial fibrillation, and a 35-pack year smoking history, presented for repair of a pseudomeningocele following a previous L1-2 laminectomy and T10-S1 hardware removal.

The procedure consisted of excising the pseudomeningocele and performing a reconstruction with bilateral trapezius muscle flaps. A 36 cm² application of STRAVIX Tissue was placed over the repair before the muscle flaps were closed. A negative pressure dressing was applied after skin closure.

The immediate follow-up was unremarkable. At one month, the patient developed a small seroma after a fall, which resolved with aspiration. Full wound closure was achieved at one month.

Case studies

Pseudomeningocele

Pre-op

Pre-op X-ray

MRI with CSF collection

Intra-op

Complete excision and hardware replacement

Intra-op

Intra-op STRAVIX◊ Tissue application

Muscle flap closure

One month post-op

The immediate follow-up was unremarkable. At one month, the patient developed a small seroma after a fall, which resolved with aspiration. Full wound closure was achieved at one month.

STRAVIX^◊

Cryopreserved Umbilical Tissue

STRAVIX PL^◊

Lyopreserved Umbilical Tissue

GRAFIX XC^◊

Cryopreserved Placental Membrane

GRAFIX PL^◊ XC

Lyopreserved Placental Membrane

OASIS^®

Matrix products**

STRAVIX^◊

Cryopreserved Umbilical Tissue

STRAVIX PL^◊

Lyopreserved Umbilical Tissue

GRAFIX XC^◊

Cryopreserved Placental Membrane

GRAFIX PL^◊ XC

Lyopreserved Placental Membrane

OASIS^®

Matrix products**

References:

Data on file at Osiris Therapeutics, Inc.
Brandeisky J, Kurtz Phelan DH. Clinical outcome of Achilles tendon repair using viable intact cryopreserved umbilical tissue versus standard of care. Wounds. 2017; 29(11): E111-E114.
Sundblad KW, Tassis EK. A quality improvement pilot assessment of the safety and associated.
McGinness K, Kurtz Phelan DH. Use of viable cryopreserved umbilical tissue for so tissue defects in patients with gas gangrene: A case series. Wounds. 2018; 30(4): 90-95.

**OASIS Matrix products are intended for management of wounds only.

Neurosurgeons and spine specialists operate in some of the most unforgiving environments in medicine. Delicate anatomy, compromised tissue, and the potential for life-altering complications demand absolute precision.

Neurosurgeons and spine specialists operate in some of the most unforgiving environments in medicine. Delicate anatomy, compromised tissue, and the potential for life-altering complications demand absolute precision.

Our advanced grafts are designed to:1-4

Case studies

Pseudomeningocele

Case studies

Pseudomeningocele

STRAVIX◊

STRAVIX PL◊

GRAFIX XC◊

GRAFIX PL◊ XC

OASIS®

STRAVIX◊

STRAVIX PL◊

GRAFIX XC◊

GRAFIX PL◊ XC

OASIS®

Our advanced grafts are designed to:^1-4

STRAVIX^◊

STRAVIX PL^◊

GRAFIX XC^◊

GRAFIX PL^◊ XC

OASIS^®

STRAVIX^◊

STRAVIX PL^◊

GRAFIX XC^◊

GRAFIX PL^◊ XC

OASIS^®