OASIS

OASIS Matrix products are naturally derived extracellular matrix (ECM) scaffolds that support the body’s ability to repair and rebuild damaged tissue.

Made from porcine small intestinal submucosa (SIS), these matrices closely resemble human dermis in both composition and function.4 They provide a biologic scaffold that promotes cellular migration, angiogenesis, and tissue regeneration.9

Why OASIS Matrix works

Simple to store, proven to perform, OASIS gives you more of what matters for managing chronic and complex wounds.

  • Similar in composition to human dermis to support natural healing pathways.4
  • Helps support the formation of granulation tissue.4,10
  • Shown to improve epithelialization and wound closure in chronic leg ulcers and diabetic foot ulcers when used with standard care.11,12
  • Sterile, shelf-stable, and versatile.
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OASIS Matrix solutions

OASIS Matrix products are designed to meet your patients where they are. That means across wound types, severity, and care settings. They are ideal for supporting closure in a variety of wounds and can be used alongside standard care protocols.11,12

The portfolio includes:

 

OASIS® Wound Matrix

A single layer of fenestrated naturally derived ECM for the shortest timeline to complete integration.

 

OASIS® Burn Matrix

Two meshed/fenestrated layers of naturally derived ECM. Extra thickness allows for easier fixation and retention of sutures and staples if necessary.

 

OASIS® Ultra Tri-layer Matrix

Three meshed/fenestrated layers of naturally derived ECM. Additional material allows for weekly visit intervals and challenging wounds with degrading enzymes.

 

OASIS® XL Matrix

Two-layer structure provides perforated layers of naturally derived ECM for 600cm2 of coverage,4  for larger surface area wounds and burns.

 

OASIS® MICRO

A micronized powder providing a conformation advantage to treat tunnelling, undermined wounds

 

Let’s talk about how OASIS products can support better outcomes for your patients and greater efficiency for your team.

 

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  1. Badylak SF. The extracellular matrix as a scaffold for tissue reconstruction:2002;13(5):377-383.
  2. Frantz, C, Stewart KM, Weaver VM. Title: The extracellular matrix at a glance, et al. J Cell Sci. 2010;123(Pt 24):4195-4200.
  3. Hodde J, Janis A, Ernst D, et al. Title: Effects of sterilization on an extracellular matrix scaffold: Part I. Composition and matrix architecture., et al.. J Mater Sci Mater Med. 2007;18(4):537-543.
  4. Data on file at Cook Biotech Incorporated.
  5. Brown B, Lindberg K, Reing J, et al. Title: The Basement Membrane Component of Biologic Scaffolds Derived from Extracellular Matrix.
  6. Hodde JP, Badylak SF, Brightman AO, Voytik-Harbin SL. Title: Glycosaminoglycan Content of Small Intestinal Submucosa: A Bioscaffold for Tissue Replacement, et al. Tissue Eng. 1996;2(3):209-217.
  7. Hurst RE, Bonner RB. Title: Mapping of the distribution of significant proteins and proteoglycans in small intestinal submucosa by fluorescence microscopy, et al. J Biomater Sci Polym Ed. 2001;12(11):1267-1279.
  8. Sottile J, Hocking DC. Title: Fibronectin Polymerization Regulates the Composition and Stability of Extracellular Matrix Fibrils and Cell-Matrix Adhesions, et al. Mol Biol Cell. 2002;13(10):3546-3559.
  9. Nihsen ES, Johnson CE, Hiles, MC. Title: Bioactivity of Small Intestinal Submucosa and Oxidized Regenerated Cellulose/Collagen, et al. Adv Skin Wound Care. 2008;21(10):479-486.
  10. Nihsen ES, Hiles, MC. Title: SMALL INTESTINAL SUBMUCOSA (SIS*) STIMULATES VEGF SECRETION IN HUMAN CELLS, et al. J Wound Ostomy Continence Nurs. 2007;34(3S):S65.
  11. Mostow EN, Haraway GD, Dalsing M, et al. Title: Effectiveness of an extracellular matrix graft (OASIS Wound Matrix) in the treatment of chronic leg ulcers: A randomized clinical trial., et al. J Vasc Surg. 2005;41(5):837-843.
  12. Cazzell SM, Lange DL, Dickerson JE, Slade HB. Title: The Management of Diabetic Foot Ulcers with Porcine Small Intestine Submucosa Tri-Layer Matrix: A Randomized Controlled Trial, et al. Adv Wound Care. 2015;4(12):711-718.