GRAFIX CORE Cryopreserved Placental Membrane

Some wounds call for maximum biologic support in the most compromised environments. GRAFIX CORE◊ Membrane is cryopreserved placental BioTissue that retains the structural and cellular integrity of fresh tissue, providing a rich biologic matrix for acute and chronic wounds.1-2

STRAVIX on blue blob

At a glance

  • Cryopreserved human placental membrane with intact extracellular matrix, growth factors, mesenchymal stem cells, fibroblasts, and epithelial cells.1,2
  • Developed for application directly to acute and chronic wounds, including deep, complex, or highly exudative sites.
  • Stored at –75 °C to –85 °C to maintain tissue integrity and long-term shelf life.

Explore the evidence

Clinical applications for cryopreserved human placental membrane

GRAFIX CORE Membrane is designed for use as a wound cover across a wide range of indications, including:

  • Chronic diabetic foot ulcers (DFUs) and venous leg ulcers (VLUs)
  • Complex post-surgical wounds with exposed tendon, bone, or hardware
  • Traumatic soft-tissue defects
  • High-risk reconstructive procedures where tissue quality is compromised

It naturally conforms to irregular anatomies and can be sutured or secured based on surgeon preference.

See how GRAFIX CORE Membrane integrates into surgical workflows
STRAVIX on blue blob

  1. Dhall S, et al. Plos One. 2018; 13 (10): e0204060. 
  2. Mamede AC, Carvalho, MJ, Abrantes AM, et al. Amniotic membrane: from structure and functions to clinical applications. Cell Tissue Res. 2012; 349 (2): 447-458.